Lymphocyte subpopulations of bone marrow of breast cancer patients
نویسندگان
چکیده
منابع مشابه
Human bone marrow lymphocytes. I. Distribution of lymphocyte subpopulations in the bone marrow of normal individuals.
This study was undertaken to determine the proportions and in vitro immune capacities of lymphocyte populations in the bone marrows of normal humans. Relatively pure mononuclear cell suspensions were obtained from bone marrow aspirates by linear sucrose gradient centrifugations. Simultaneous peripheral blood and bone marrow specimens from each individual were assayed for lymphocyte surface mark...
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PURPOSE Pathologic angiogenesis has been correlated with tumor growth, dissemination, metastasis, and prognosis in solid tumors including breast cancer. Angiogenesis has also been implicated in the pathophysiology of, and shown to be a therapeutic target in tumors arising in the bone marrow. The status of angiogenesis in the bone marrow of breast cancer patients is unknown. The aim of this stud...
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Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
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Human brucellosis is a major health problem in developing countries. A number of patients with human brucellosis do not recover from the acute stage of the disease and pass into the chronic form. Since the pathophysiology of this change is not well understood, we studied the T-cell subsets during the acute, subacute and chronic forms of human brucellosis. In this study we found alterations...
متن کاملMarrow of Breast Cancer Patients
Background: Contamination of bone marrow andperipheral blood stem cells withtumorcells is a problem thatmaybe encountered when autologous hematopoietic stem cell transplantation is conducted concurrently with high-dose chemotherapy. Methods: Using monoclonal antibodies to a variety of tumors, thedetection of tumorcells in the bone marrow of breast cancer patients was studied by immunohistochemi...
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ژورنال
عنوان ژورنال: Tumors of female reproductive system
سال: 2015
ISSN: 1999-8627,1994-4098
DOI: 10.17650/1994-4098-2015-11-2-52-55